High Throughput
Screening (HTS) refers to a scientific experimentation method used in
the process of drug discovery. HTS enables automated assays of
biological or biochemical activity of compounds similar to drugs.
These assays facilitate discovery of enzymes, ligands for receptors
and other pharmacological tests. In addition this process aids in
rapid identification of antibodies, genes or active compounds that
are responsible for alteration of a specific biomolecular pathway.
Presently, the HTS industry is expected to reduce the costs involved
in drug discovery process and release the potential lead compounds
resultant from screening campaigns. This expectation led HTS industry
to adopt smarter screening procedures by screening only focused and
potential compounds along with the use of highly efficient
instrumentation platforms.
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The HTS industry
poses a competitive environment, with regular technology transfers
and information sharing between the market rivals. With the
increasing competition between the pharma companies to pioneer the
drug commercialization, the need for HTS increases simultaneously, as
this reduces the overall time required for commercializing the drug
molecules. HTS market promises affirmative growth potential in near
future due to its inevitable use in the research and production
fields and can be segmented by technology, applications and
geography. Some of the technological advances in the HTS industry
attribute to introduction of high content screening technologies,
miniaturization of the HTS technological platforms and novel cell
culture approaches.
The major factors
positively impacting the growth of the market accounts for continuous
HTS technological upgradations, rigorous research and development
initiatives, increase in investments by the drug discovery firms and
focus on development of
robust hardware and software used in screening. On the other hand
increasing demand for highly efficient biochemical assays, need for
cost effective solutions and negative impacts of economic slowdown on
HTS outsourcing might hamper the growth of HTS market. Some of the
major players competing in this market are Agilent Technologies,
Inc., Aurora Biomed, Inc., Sigma-Aldrich Corporation, Life
Technologies Corporation, Luminex Corporation, Beckman Coulter, Inc.,
and Roche Applied Sciences.
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