Angiogenesis is a
physiological process that is associated withthe formation of new blood vessel
from existing blood vessels. Angiogenesis process is commonly categorized into
two types namely sprouting angiogenesis and intussusceptive angiogenesis.
Sprouting angiogenesis is a fundamental mechanism of vessel growth in which
formation of new blood vessel is regulated by sequential steps. Intussusceptive
angiogenesis (also called as splitting angiogenesis) is referred where new
blood vessel is created by internal division of an existing blood vessel.
In contrast to
sprouting angiogenesis, intussusceptive do not need local endothelial cell
proliferation. Angiogenesis is mainly associated with the diverse set of
conditions such as age related macular degradation, rheumatoid arthritis,
cancer and psoriasis.The main focus of angiogenesis therapy is to shrink the
existing tumor by aninhibitor or to meet the demand of under perfused region
through generating new vessels by angiogenesis stimulator. Avastin
(bevacizumab), Gleevec, Tarceva and Iressa are some of the largest selling
angiogenesis inhibitor drugs worldwide.
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Research and
development activitiesfor the development of novel angiogenesis drugs for
cancer treatment is the highest.Thus, increasing number of cancer cases will
drive the growth of this market during the forecast period. According to World
Health Organization, approximately 8.2 million deaths are reported in the year
of 2012 due to cancer. Also it is predicted that, the annual cancer cases are
expected rise from14 million to 22 million in next two decades. In addition,
National Cancer Institute states that there are approximately 1,660,290 cases
reported in the United States in 2013.Technological advancement will further
boost the growth of angiogenesis inhibitor and stimulatorsmarket.For example,
research in angiogenesis has enabled identification of several angiogenesis
agonist and antagonist. However, high cost of these drugs will restrain the
growth of this market.
Geographically, North
America represents the largest market, followed by Europe for angiogenesis
inhibitors and stimulatorsdue to large patient base and rise in treatment seeking
population in these regions. The market of angiogenesis inhibitors and
stimulators in Asia-Pacific countries such as India and China, South East Asian
countries holds a strong growth as there is a rise in total number of newly
diagnosed patient population of cancer in this region. According to World
Health Organization, 60% of the world’s total annual cases of cancer occur in
Africa, Asia and South America.
Some of the key players
in the Angiogenesis Inhibitors and Stimulators market comprises Abbott
Laboratories, Adnexus Therapeutics, Inc., F. Hoffman-La Roche, Ltd., Genentech,
Inc., Amgen, Inc., AstraZeneca Plc., Novartis AG, Pfizer, Inc., Chugai Pharmaceutical
Co., Ltd., EntreMed, Inc. and Eyetech, Inc.
This research report
analyzes this market depending on its market segments, major geographies, and
current market trends.
Geographies analyzed under this research report
include
- North America
- Asia Pacific
- Europe
- Rest of the World
This report provides
comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming
years
This report is a
complete study of current trends in the market, industry growth drivers, and
restraints. It provides market projections for the coming years. It includes
analysis of recent developments in technology, Porter’s five force model
analysis and detailed profiles of top industry players. The report also
includes a review of micro and macro factors essential for the existing market
players and new entrants along with detailed value chain analysis.
Reasons for Buying this Report
- This report provides pin-point
analysis for changing competitive dynamics
- It provides a forward looking
perspective on different factors driving or restraining market
growth
- It provides a technological growth
map over time to understand the industry growth rate
- It provides a seven-year forecast
assessed on the basis of how the market is predicted to grow
- It helps in understanding the key
product segments and their future
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